Proteomics Post-doc

Website Newcastle University Biosciences Institute

Matthias Trost has two post-doc positions in proteomics available within his Wellcome Investigator Award.

The successful applicants will utilise state-of-the-art proteomics to study how innate immune responses triggered by bacterial infection of macrophages are regulated by ubiquitylation. Ubiquitylation is an important post-translational modification regulating all biology, including inflammation and cancer. We have recently identified key E3 ligases regulating phagosome functions and the project will characterise the molecular mechanisms of these E3 ligases. The project will exploit the laboratory’s expertise in proteomics, biochemistry and cell biology techniques.

I seek talented and enthusiastic post-doctoral scientists with a background in quantitative mass spectrometry and proteomics. The successful applicants will have a good academic track record and have published at least one first authored paper in an international journal. The candidates will ideally have experience with ubiquitylation or other post-translational modifications. Knowledge and working experience in cell biological and biochemical techniques would be advantageous but is not essential.

The positions are available for up to 5 years. Available immediately, but applicants wishing to start at a later time will be considered.

The positions are based in the Newcastle University Biosciences Institute (NUBI). In the last Research Excellence Framework (REF2014) by the UK government, our institute (then called ICaMB) was 1st for research output amongst all of the UK submitted university biosciences departments and was placed 5th out of 44 UK submissions in the overall scores.

Newcastle upon Tyne is a vibrant city in the northeast of England. In addition to an excellent scientific environment, Newcastle offers an affordable standard of living in an area of outstanding natural beauty with beautiful beaches at the coast and Northumberland countryside.

NUBI is committed to the Athena SWAN Charter for Women in Science as detailed on our web site ( and have recently received a Silver Award from Athena Swan.

Further information can be obtained by contacting Prof Matthias Trost ( or from the lab’s website:

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