Senior Scientist, Quantitative Proteomics

Website University of Massachusetts Medical School Mass Spectrometry Facility

A Senior Research Scientist position focusing on quantitative proteomics is available at the Mass Spectrometry Facility at the University of Massachusetts Medical School. Affiliated with the Department of Biochemistry and Molecular Pharmacology, the Facility supports projects in basic and translational science across a diverse range of applications in proteomics, structural biology, metabolomics, small molecule quantitation, and mass spectrometry imaging. There are nine mass spectrometry platforms including four Orbitraps (Thermo Fusion Lumos w/ ETD and FAIMS, Q Exactive HF-X, Q Exactive and Orbitrap Velos Pro), a Q-TOF (Waters Synapt G2-Si) and two triple quadrupoles (Waters Xevo TQ-XS and Thermo TSQ Quantiva), all located in a spacious 5,000 sq. ft facility. This is a unique growth opportunity for an enthusiastic self-starter that will contribute to a wide and diverse range of projects both within the University of Massachusetts and to the external scientific community at large. The individual will be responsible for aspects of project planning, method development, sample preparation, data acquisition and bioinformatics. Responsibilities also include providing client/collaborator project support, consulting and teaching practical interpretation of proteomic datasets, effectively communicating project progress, writing technical summaries, preparing presentations, and participating in publication and grant writing. Importantly, the individual will be expected to evaluate and optimize new proteomics technologies including those relevant to sample preparation, chromatography, data acquisition and software/data analysis.

The successful candidate will have significant background in proteomics and can demonstrate a clear record of publication. Proficiency in bioinformatics approaches including protein quantification, statistical analyses, and pathway analysis is required. Programming experience would be considered a plus. Direct experience with data-independent acquisition datasets is highly desired. The successful candidate must be highly motivated, interested in expanding their background while working in an interdisciplinary collaborative environment, and willing to work with a highly diverse clientele. Outstanding oral and written communication skills are essential. The Mass Spectrometry Facility is a team-oriented environment and individuals must be able to handle various projects simultaneously through multi-tasking and prioritization. Candidates with a PhD (Chemistry, Biochemistry or related discipline) are preferred and must have a minimum of 5 years of relevant working experience beyond degree (Masters with 5+ years of experience will be considered). Review of applications will begin immediately, and the position will remain open until filled. When submitting your CV, please include a cover letter detailing your interest in the position and specifically address how the opportunity fits with your career goals. As an equal opportunity and affirmative action employer, UMMS recognizes the power of a diverse community and encourages applications from individuals with varied experiences, perspectives and backgrounds.

For immediate consideration, send CV and cover letter to:

To apply for this job email your details to